Side Effects, Dosage, Uses & More

Serotonin syndrome: This drug could trigger a probably life-threatening situation referred to as serotonin syndrome. The signs of serotonin syndrome embody hallucinations and delusions, agitation, coma, quick coronary heart charge, and adjustments in blood strain. In addition they embody dizziness, lack of consciousness, seizures, shakiness, muscle tremor or stiff muscle groups, sweating, nausea, and vomiting.

  • Extreme allergic response: This drug can generally trigger a extreme allergic response. Name 911 or go to the emergency room immediately you probably have swelling of your face, tongue, or throat, or you’ve hassle respiratory. A extreme allergic response could trigger demise. You shouldn’t take this medicine once more you probably have ever had an allergic response to it.
  • Elevated bleeding: This drug could improve your danger for bleeding or bruising if used with aspirin, nonsteroidal anti-inflammatory medication (NSAIDs), equivalent to ibuprofen or naproxen, or the blood thinner warfarin. Speak together with your physician when you’re taking or planning to take any prescription or over-the-counter medicines that improve the danger of bleeding.
  • Sexual issues (dysfunction): This drug could trigger sexual issues. Signs could embody decreased intercourse drive, delayed orgasm or lack of ability to have an orgasm, issues getting or preserving an erection, and ejaculation issues. Contact your physician when you expertise any adjustments in sexual perform.

Sertraline oral pill is a prescription drug that’s out there because the brand-name drug Zoloft. It’s additionally out there as a generic drug. Generic medication normally value much less. In some circumstances, they will not be out there in each power or kind because the brand-name model. This drug can be out there as an oral answer.

Why it’s used

This drug is used to deal with main depressive dysfunction, obsessive-compulsive dysfunction, panic dysfunction, post-traumatic stress dysfunction, social nervousness dysfunction, and premenstrual dysphoric dysfunction.

This drug could also be used as a part of a mixture remedy. This implies it’s possible you’ll have to take it with different medicines.

The way it works

This drug belongs to a category of medication referred to as selective serotonin reuptake inhibitors. A category of medication is a bunch of medicines that work in the same means. These medication are sometimes used to deal with related situations.

This drug works by growing the quantity of serotonin, a pure substance in your mind, that helps preserve psychological well being stability. This may enhance the signs of melancholy and nervousness.

Sertraline oral pill could trigger drowsiness, insomnia, or each. It could additionally trigger different unwanted effects.

Extra widespread unwanted effects

The grownup unwanted effects for this drug are barely totally different from the unwanted effects for youngsters. Unwanted effects for adults and youngsters can embody:

  • nausea, lack of urge for food, diarrhea, and indigestion
  • change in sleep habits, together with elevated sleepiness and insomnia
  • elevated sweating
  • sexual issues, together with decreased intercourse drive and ejaculation failure
  • tremor or shaking
  • tiredness and fatigue
  • agitation

Extra unwanted effects for youngsters can embody:

  • irregular improve in muscle motion or agitation
  • nostril bleed
  • extra frequent urination
  • urine leakage
  • aggressiveness
  • heavy menstrual intervals
  • slowed development charge and weight change. It is best to carefully watch your baby’s top and weight whereas they take this drug.

If these results are delicate, they might go away inside a number of days or a few weeks. In the event that they’re extra extreme or don’t go away, discuss to your physician or pharmacist.

Severe unwanted effects

Name your physician immediately you probably have severe unwanted effects. Name 911 in case your signs really feel life-threatening or when you assume you’re having a medical emergency. Severe unwanted effects and their signs can embody the next:

  • Suicide makes an attempt
  • Performing on harmful impulses
  • Aggressive or violent habits
  • Ideas about suicide or dying
  • New or worse melancholy
  • New or worse nervousness or panic assaults
  • Agitation, restlessness, anger, or irritability
  • Hassle sleeping
  • A rise in exercise or speaking greater than regular
  • Serotonin syndrome. This situation might be life-threatening. Signs can embody:
    • hallucinations and delusions
    • agitation
    • lack of consciousness
    • seizures
    • coma
    • quick coronary heart charge
    • adjustments in blood strain
    • muscle tremor or stiff muscle groups
    • dizziness
    • shakiness
    • sweating
    • nausea
    • vomiting
    • muscle rigidity
  • Extreme allergic reactions. Signs can embody:
    • hassle respiratory
    • swelling of your face, tongue, eyes, or mouth
    • rash, itchy welts (hives) or blisters, alone or with fever or joint ache
  • Irregular bleeding
  • Seizures or convulsions
  • Manic episodes. Signs can embody:
    • significantly elevated vitality
    • extreme hassle sleeping
    • racing ideas
    • reckless habits
    • unusually grand concepts
    • extreme happiness or irritability
    • speaking extra or quicker than typical
  • Modifications in urge for food or weight. It is best to examine the load and top of youngsters and adolescents typically whereas they take this drug.
  • Low sodium ranges. Seniors could also be at larger danger for this. Signs can embody:
    • headache
    • weak spot or unsteadiness
    • confusion, issues concentrating or pondering, or reminiscence issues
  • Eye ache
  • Modifications in imaginative and prescient, together with blurred and double imaginative and prescient
  • Swelling or redness in or round your eyes

Disclaimer: Our objective is to offer you essentially the most related and present info. Nevertheless, as a result of medication have an effect on every individual in a different way, we can’t assure that this info consists of all potential unwanted effects. This info will not be an alternative choice to medical recommendation. All the time focus on potential unwanted effects with a healthcare supplier who is aware of your medical historical past.

Sertraline oral pill can work together with different medicines, nutritional vitamins, or herbs it’s possible you’ll be taking. An interplay is when a substance adjustments the way in which a drug works. This may be dangerous or forestall the drug from working nicely.

To assist keep away from interactions, your physician ought to handle all your medicines rigorously. Remember to inform your physician about all medicines, nutritional vitamins, or herbs you’re taking. To learn how this drug would possibly work together with one thing else you’re taking, discuss to your physician or pharmacist.

Medication you shouldn’t use with sertraline

Don’t take these medication with sertraline. When they’re used with sertraline, they’ll trigger harmful results in your physique. These medication embody:

  • Pimozide. Taking this drug with sertraline may cause severe coronary heart issues.
  • Monoamine oxidase inhibitors (MAOIs) equivalent to isocarboxazid, phenelzine, and tranylcypromine. Taking these medication with sertraline will increase your danger for serotonin syndrome. It’s essential to additionally wait 14 days between taking these medication and taking sertraline.
  • Linezolid, intravenous methylene blue. Taking this medication with sertraline will increase your danger for serotonin syndrome.

Interactions that improve the danger of unwanted effects

Taking sure medicines with sertraline could lead to elevated unwanted effects. These medication embody:

  • Nonsteroidal anti-inflammatory medication (NSAIDs) equivalent to ibuprofen, naproxen, aspirin and warfarin. Taking these medication with sertraline will increase your danger for bleeding or bruising.
  • Triptans equivalent to sumatriptan. Your danger for serotonin syndrome is elevated whenever you take these medication with sertraline. Your physician ought to watch you carefully when you take these medication collectively.
  • Lithium. Taking this drug with lithium will increase your danger for serotonin syndrome.
  • Serotonergic medicines equivalent to fentanyl, tramadol, and St John’s wort. Taking these medication with sertraline will increase your danger for serotonin syndrome.
  • Cimetidine. Taking cimetidine with sertraline could trigger a build-up of sertraline in your physique. Your dose of sertraline would possibly must be lowered when you take it with cimetidine.
  • Tricyclic antidepressants equivalent to amitriptyline, desipramine, and imipramine. Taking sertraline with these medication could trigger these medication to construct up in your physique. Your physician might have to regulate your dosage of tricyclic antidepressants when you take sertraline.

Disclaimer: Our objective is to offer you essentially the most related and present info. Nevertheless, as a result of medication work together in a different way in every individual, we can’t assure that this info consists of all potential interactions. This info will not be an alternative choice to medical recommendation. All the time converse together with your healthcare supplier about potential interactions with all pharmaceuticals, nutritional vitamins, herbs and dietary supplements, and over-the-counter medication that you’re taking.

Sertraline oral pill comes with a number of warnings.

Allergy warning

This drug may cause a extreme allergic response. Signs can embody:

  • hassle respiratory
  • swelling of your face, tongue, eyes, or mouth
  • rash, itchy welts (hives) or blisters, alone or with fever or joint ache

When you’ve got an allergic response, name your physician or native poison management heart immediately. In case your signs are extreme, name 911 or go to the closest emergency room.

Don’t take this drug once more when you’ve ever had an allergic response to it. Taking it once more might be deadly (trigger demise).

Alcohol interplay

Ingesting alcohol when you take sertraline can improve your danger for sleepiness. It might additionally have an effect on your potential to make selections, assume clearly, or react shortly. For those who drink alcohol, discuss to your physician.

Warnings for individuals with sure well being situations

For individuals with glaucoma: Taking this drug could set off a glaucoma assault. When you’ve got glaucoma, discuss to your physician earlier than taking this drug.

For individuals with bipolar dysfunction: Taking this drug could set off a manic episode. When you’ve got a historical past of mania or bipolar dysfunction, discuss to your physician earlier than utilizing this drug.

For individuals with seizures: Taking this drug will increase your danger for seizures. If you have already got seizures, discuss to your physician earlier than taking this drug. When you’ve got a seizure whereas utilizing this drug, you need to cease taking it.

For individuals with kidney issues: When you’ve got kidney issues or a historical past of kidney illness, it’s possible you’ll not be capable to clear this drug out of your physique nicely. This may occasionally improve the degrees of this drug in your physique and trigger extra unwanted effects. This drug may lower your kidney perform, making your kidney illness worse.

For individuals with liver issues: When you’ve got liver issues or a historical past of liver illness, your physique could not be capable to course of this drug as nicely. This may occasionally improve the degrees of this drug in your physique and trigger extra unwanted effects.

Warnings for different teams

For pregnant ladies: This drug is a class C being pregnant drug. Which means two issues:

  1. Analysis in animals has proven hostile results to the fetus when the mom takes the drug.
  2. There haven’t been sufficient research accomplished in people to make certain how the drug would possibly have an effect on the fetus.

Speak to your physician when you’re pregnant or planning to grow to be pregnant. This drug ought to solely be used if the potential profit justifies the potential danger to the fetus. Name your physician immediately when you grow to be pregnant whereas taking this drug.

For girls who’re breastfeeding: This drug could go into breast milk and should trigger unwanted effects in a toddler who’s breastfed. Speak to your physician when you breastfeed your baby. Chances are you’ll have to determine whether or not to cease breastfeeding or cease taking this medicine.

For seniors: The kidneys of older adults could not work in addition to they used to. This may trigger your physique to course of medication extra slowly. Consequently, extra of a drug stays in your physique for an extended time. This raises your danger for unwanted effects. In case you are over the age of 65 years, it’s possible you’ll be at larger danger for growing muscle issues whereas taking this drug, together with low salt ranges within the blood (referred to as hyponatremia).

For kids: This medicine has not been studied in youngsters as a therapy for main depressive dysfunction, panic dysfunction, post-traumatic dysfunction, social nervousness dysfunction, and premenstrual dysphoric dysfunction. It shouldn’t be used for these issues in individuals youthful than 18 years.

This medicine has solely been studied in youngsters with obsessive-compulsive dysfunction. For therapy of obsessive-compulsive dysfunction, it shouldn’t be utilized in individuals youthful than 6 years.

This dosage info is for sertraline oral pill. All potential dosages and drug types will not be included right here. Your dosage, drug kind, and the way typically you’re taking the drug will rely on:

  • your age
  • the situation being handled
  • how extreme your situation is
  • different medical situations you’ve
  • the way you react to the primary dose

Types and strengths

Generic: sertraline

  • Type: Oral pill
  • Strengths: 25 mg, 50 mg, 100 mg
  • Type: Oral answer
  • Strengths: 20 mg/mL

Model: Zoloft

  • Type: Oral pill
  • Strengths: 25 mg, 50 mg, 100 mg
  • Type: Oral answer
  • Strengths: 20 mg/mL

Dosage for main depressive dysfunction

Grownup dosage (ages 18–64 years)

  • The everyday beginning dose is 50 mg per day.
  • Your physician will slowly improve your dose each week, as wanted.
  • The utmost dose is 200 mg per day.

Little one dosage (ages 0–17 years)

Using this drug to deal with youngsters with this situation has not been studied. It shouldn’t be utilized in individuals youthful than 18 years.

Senior dosage (ages 65 years and older)

The kidneys of older adults could not work in addition to they used to. This may trigger your physique to course of medication extra slowly. Consequently, extra of a drug stays in your physique for an extended time. This raises your danger for unwanted effects. Your physician could begin you on a lowered dose or a unique dosing schedule. This might help hold ranges of this drug from increase an excessive amount of in your physique.

Dosage for obsessive-compulsive dysfunction

Grownup dosage (ages 18–64 years)

  • The everyday beginning dose is 50 mg per day.
  • Your physician will slowly improve your dose each week, as wanted.
  • The utmost dose is 200 mg per day.

Little one dosage (ages 0–5 years)

Using this drug to deal with this situation in youngsters hasn’t been studied. It shouldn’t be utilized in individuals youthful than 6 years.

Little one dosage (ages 6–12 years)

  • The everyday beginning dose is 25 mg per day.
  • Your physician will slowly improve your dose each week, as wanted.
  • The utmost dose is 200 mg per day.

Little one dosage (ages 13–17)

  • The everyday beginning dose is 50 mg per day.
  • Your physician will slowly improve your dose each week, as wanted.
  • The utmost dose is 200 mg per day.

Senior dosage (ages 65 years and older)

The kidneys of older adults could not work in addition to they used to. This may trigger your physique to course of medication extra slowly. Consequently, extra of a drug stays in your physique for an extended time. This raises your danger for unwanted effects. Your physician could begin you on a lowered dose or a unique dosing schedule. This might help hold ranges of this drug from increase an excessive amount of in your physique.

Dosage for panic dysfunction

Grownup dosage (ages 18–64 years)

  • The everyday beginning dose is 25 mg per day. That is normally elevated to 50 mg per day after 1 week.
  • Your physician will slowly improve your dose each week, as wanted.
  • The utmost dose is 200 mg per day.

Little one dosage (ages 0–17 years)

Using this drug to deal with youngsters with this situation has not been studied. It shouldn’t be utilized in individuals youthful than 18 years.

Senior dosage (ages 65 years and older)

The kidneys of older adults could not work in addition to they used to. This may trigger your physique to course of medication extra slowly. Consequently, extra of a drug stays in your physique for an extended time. This raises your danger for unwanted effects. Your physician could begin you on a lowered dose or a unique dosing schedule. This might help hold ranges of this drug from increase an excessive amount of in your physique.

Dosage for post-traumatic stress dysfunction

Grownup dosage (ages 18–64 years)

  • The everyday beginning dose is 25 mg per day. That is normally elevated to 50 mg per day after 1 week.
  • Your physician will slowly improve your dose each week, as wanted.
  • The utmost dose is 200 mg per day.

Little one dosage (ages 0–17 years)

Using this drug to deal with youngsters with this situation has not been studied. It shouldn’t be utilized in individuals youthful than 18 years.

Senior dosage (ages 65 years and older)

The kidneys of older adults could not work in addition to they used to. This may trigger your physique to course of medication extra slowly. Consequently, extra of a drug stays in your physique for an extended time. This raises your danger for unwanted effects. Your physician could begin you on a lowered dose or a unique dosing schedule. This might help hold ranges of this drug from increase an excessive amount of in your physique.

Dosage for social nervousness dysfunction

Grownup dosage (ages 18–64 years)

  • The everyday beginning dose is 25 mg per day. That is normally elevated to 50 mg per day after 1 week.
  • Your physician will slowly improve your dose each week, as wanted.
  • The utmost dose is 200 mg per day.

Little one dosage (ages 0–17 years)

Using this drug to deal with youngsters with this situation has not been studied. It shouldn’t be utilized in individuals youthful than 18 years.

Senior dosage (ages 65 years and older)

The kidneys of older adults could not work in addition to they used to. This may trigger your physique to course of medication extra slowly. Consequently, extra of a drug stays in your physique for an extended time. This raises your danger for unwanted effects. Your physician could begin you on a lowered dose or a unique dosing schedule. This might help hold ranges of this drug from increase an excessive amount of in your physique.

Dosage for premenstrual dysphoric dysfunction

Grownup dosage (ages 18–64 years)

The everyday beginning dose is 50 mg per day, all through your menstrual cycle.

Little one dosage (ages 0–17 years)

Using this drug to deal with youngsters with this situation has not been studied. It shouldn’t be utilized in individuals youthful than 18 years.

Senior dosage (ages 65 years and older)

The kidneys of older adults could not work in addition to they used to. This may trigger your physique to course of medication extra slowly. Consequently, extra of a drug stays in your physique for an extended time. This raises your danger for unwanted effects. Your physician could begin you on a lowered dose or a unique dosing schedule. This might help hold ranges of this drug from increase an excessive amount of in your physique.

Disclaimer: Our objective is to offer you essentially the most related and present info. Nevertheless, as a result of medication have an effect on every individual in a different way, we can’t assure that this record consists of all potential dosages. This info will not be an alternative choice to medical recommendation. All the time to talk together with your physician or pharmacist about dosages which are best for you.

Sertraline oral pill is used for long-term therapy. It comes with severe dangers when you don’t take it as prescribed.

For those who cease taking the drug instantly or don’t take it in any respect: Your melancholy won’t get higher. It could even worsen. Don’t cease taking this drug with out first speaking to your healthcare supplier. Stopping your drug too shortly could trigger severe signs, together with:

  • nervousness, irritability, excessive or low temper, restlessness, and adjustments in your sleep habits
  • headache, sweating, nausea, and dizziness
  • electrical shock-like sensations, shaking, and confusion

For those who miss doses or don’t take the drug on schedule: Your medicine could not work as nicely or could cease working fully. For this drug to work nicely, a specific amount must be in your physique always.

For those who take an excessive amount of: You might have harmful ranges of the drug in your physique. Signs of an overdose of this drug can embody:

  • tiredness
  • vomiting
  • quick coronary heart charge
  • nausea
  • dizziness
  • agitation
  • tremors

For those who assume you’ve taken an excessive amount of of this drug, name your physician or native poison management heart. In case your signs are extreme, name 911 or go to the closest emergency room immediately.

What to do when you miss a dose: Take your dose as quickly as you bear in mind. However when you bear in mind only a few hours earlier than your subsequent scheduled dose, take just one dose. By no means attempt to catch up by taking two doses directly. This might lead to harmful unwanted effects.

How you can inform if the drug is working: You’ll know that this drug is working when you discover that your melancholy signs are much less extreme or occur much less typically. This may occasionally take as much as 4 weeks. Once you do begin to really feel higher, don’t cease taking it. Proceed to take it as your physician informed you.

Maintain these issues in thoughts in case your physician prescribes sertraline oral pill for you.

Common

  • You possibly can take this drug with or with out meals.
  • You possibly can lower or crush the pill.
  • Not each pharmacy shares this drug. When filling your prescription, make sure you name forward.

Storage

  • Retailer this drug at room temperature between 59°F and 86°F (15°C and 30°C). Maintain it away from gentle.
  • Don’t retailer this medicine in moist or damp areas, equivalent to loos.
  • Maintain the bottle closed tightly.

Refills

A prescription for this medicine is refillable. You shouldn’t want a brand new prescription for this medicine to be refilled. Your physician will write the variety of refills licensed in your prescription.

Journey

All the time carry your medication with you whenever you journey.

  • When flying, by no means put it right into a checked bag. Maintain it in your carry-on bag.
  • Don’t fear about airport x-ray machines. They’ll’t harm your medicine.
  • Chances are you’ll want to point out airport workers the pharmacy label on your medicine. All the time carry the unique prescription-labeled field with you.
  • Don’t put this medicine in your automobile’s glove compartment or go away it within the automobile. Remember to keep away from doing this when the climate could be very sizzling or very chilly.

Medical monitoring

Your physician will monitor you for sure well being points. That is accomplished to ensure you keep secure when you take this drug. Your physician will examine:

  • Your psychological well being and signs of melancholy. Your physician will monitor your signs of melancholy to ensure that this drug is working and that you just’re not having suicidal ideas. They’ll watch you carefully through the first few months after you begin taking this drug or you probably have had dose adjustments.
  • Sodium ranges. Your physician could examine the quantity sodium in your physique. Your physician could do that whenever you begin utilizing this drug and at different instances if you are taking it.
  • Eye strain. Your physician could examine the strain of your eyes frequently when you take this drug. Your physician will do that you probably have a historical past of elevated eye strain or are in danger for sure forms of glaucoma.
  • Levels of cholesterol. This drug can improve your ldl cholesterol. Your physician will examine your levels of cholesterol to ensure that they aren’t getting too excessive.
  • Liver perform. Your physician will examine how nicely your liver is working when you take this drug. In case your liver isn’t working nicely, your physician could determine to decrease your dose of this drug.

Insurance coverage

Many insurance coverage firms require a previous authorization for this drug. This implies your physician might want to get approval out of your insurance coverage firm earlier than your insurance coverage firm pays for the prescription.

There are different medication out there to deal with your situation. Some could also be higher suited to you than others. Speak to your physician about different drug choices which will be just right for you.

Disclaimer: Healthline has made each effort to make sure that every one info is factually appropriate, complete, and up-to-date. Nevertheless, this text shouldn’t be used as an alternative choice to the information and experience of a licensed healthcare skilled. It is best to all the time seek the advice of your physician or different healthcare skilled earlier than taking any medicine. The drug info contained herein is topic to vary and isn’t meant to cowl all potential makes use of, instructions, precautions, warnings, drug interactions, allergic reactions, or hostile results. The absence of warnings or different info for a given drug doesn’t point out that the drug or drug mixture is secure, efficient, or applicable for all sufferers or all particular makes use of.

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